After being diagnosed with terminal cancer on the same day his girlfriend (Monica Baccarin) accepts his marriage proposal, former Special Ops agent Wade Wilson (Ryan Reynolds) is approached by a shady organization offering a cure to his cancer. Wade accepts and meets a psychopath, Ajax, actually Francis Freeman, (Ed Skrein) who injects Wade with a strange serum, supposedly the cure to his cancer. Francis, along with his assistant Angel Dust (Gina Cariano) proceed to put Wade through unbearable torture, leaving him with horrible burn-like scars in his entire body and an accelerated healing factor. But Wade doesn't forget, as he's pissed and wants his face back to normal. Armed with two katanas, pistols, and a red suit and mask, Wade becomes Deadpool, and makes it his mission to hunt Francis down and get revenge.